Preparation of orally disintegrated membranes from liquorice inclusion complexes

Objective: to prepare and evaluate orally disintegrating films of liquorice inclusion complexes. Methods: the active components Chinese were extracted by pressurised extraction technique, complexes prepared antisolvent method, while buccal disintegration solvent casting evaluated. Results: home-made disintegrated formed better films, had good hardness toughness, thickness was around 0.1 mm could disintegrate within 40 s, dissolution rapid, cumulative release reached 80.1% 10 min, reaching immediate effect. Conclusion: membranes complexes, which are expected provide new ideas for development study other drugs in future, deserve further investigation.